Airway surface liquid pH is not acidic in children with cystic fibrosis

oleh: André Schultz, Ramaa Puvvadi, Sergey M. Borisov, Nicole C. Shaw, Ingo Klimant, Luke J. Berry, Samuel T. Montgomery, Thien Nguyen, Silvia M. Kreda, Anthony Kicic, Peter B. Noble, Brian Button, Stephen M. Stick

Format: Article
Diterbitkan: Nature Portfolio 2017-11-01

Deskripsi

Modulation of airway surface liquid pH has been proposed as a therapy for cystic fibrosis, but whether pH is indeed altered in cystic fibrosis is controversial. Here, the authors develop a novel fibre-optic based pH measurement technology, and show that pH is not altered in children with cystic fibrosis.