FERARI and cargo adaptors coordinate cargo flow through sorting endosomes

oleh: Jachen A. Solinger, Harun-Or Rashid, Anne Spang

Format: Article
Diterbitkan: Nature Portfolio 2022-08-01

Deskripsi

It is estimated that about 80% of endocytosed material is recycled back to the plasma membrane. Here, the authors show that kiss-and-run of Rab5 early endocytic and Rab11 recycling vesicles on sorting endosomes allow cargo flow, providing more robustness and fidelity to the sorting process.