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The OPERA experiment was designed to study muon neutrino to tau neutrino oscillations in appearance mode, using the CERN to Gran Sasso (CNGS) high energy neutrino beam 730 km far from the source. From 2008 to 2012, CNGS neutrinos interactions were recorded in the OPERA detector, which includes target units made of lead plates alternated with emulsion films and electronic tracker planes. The on-going analysis is aimed at the detection of short-lived particle decays occurring over distances of the order of 1 mm from the neutrino interaction point. It has allowed identifying charmed hadrons together with the tau lepton decay candidates that have established vμ → vτ oscillations with a significance of 4.2 σ. The procedure applied in OPERA to detect short-lived particle decays and its application to the search for charmed hadrons will be discussed here in detail.