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Brønsted acid-catalysed enantioselective construction of axially chiral arylquinazolinones
oleh: Yong-Bin Wang, Sheng-Cai Zheng, Yu-Mei Hu, Bin Tan
Format: | Article |
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Diterbitkan: | Nature Portfolio 2017-05-01 |
Deskripsi
Axially chiral arylquinazolinones are structural motifs in several natural products and can also act as chiral ligands. Here, the authors show a chiral phosphoric acid-catalysed strategy to access enantiomerically pure arylquinazolinones by efficient transfer of central chirality into axial chirality.