Superoxide Anions Inhibit Intracellular Calcium Response in Porcine Airway Smooth Muscle Cells
oleh: Ramesh Krishnan, Mathur S. Kannan, Deepak A. Deshpande
| Format: | Article |
|---|---|
| Diterbitkan: | Thieme Medical Publishers, Inc. 2024-04-01 |
Deskripsi
Background Superoxide anions (O2 −) have multiple effects on pulmonary parenchyma altering cell proliferation, cellular metabolism, and airway smooth muscle (ASM) contraction. Intracellular calcium ([Ca2+]i) concentration plays a significant role in the regulation of ASM contraction, relaxation, proliferation, and gene expression.