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Campylobacter species were isolated from chicken meats in northeastern Thailand from December, 2007 to June,2008. From 1,930 samples, Campylobacter spp. were obtained from 556 (28.8%). Campylobacter species were isolated fromchicken livers at higher percentages compared to the other parts of chicken meats (p<0.001). Among 294 Campylobacterisolates, 187 (63.6%) were identified as C. jejuni, and 107 (36.4%) as C. coli. The results of serotyping by Penner’s methodshowed that serotype L (22.7%) and serotype A (18.7%) were predominant. Antimicrobial susceptibility test revealed that90.7, 37.3, 29.3 and 13.3% of C. jejuni were resistant to OFLX, DOXY, EM and CP, respectively. MIC50/MIC90 of OFLX, DOXY,EM and CP were 16/128, 4/256, 0.5/128 and 2/64 μg/ml, respectively. Precaution needs to be emphasized when attempt to useOFLX and DOXY for veterinary and human medicine due to the high percentage of resistance among C. jejuni isolated fromchicken meat origin. These alarming figures should be notified to the general public.