Selective labelling and eradication of antibiotic-tolerant bacterial populations in Pseudomonas aeruginosa biofilms
oleh: Song Lin Chua, Joey Kuok Hoong Yam, Piliang Hao, Sunil S. Adav, May Margarette Salido, Yang Liu, Michael Givskov, Siu Kwan Sze, Tim Tolker-Nielsen, Liang Yang
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-02-01 |
Deskripsi
Pathogenic bacteria can aggregate to form biofilms and develop tolerance to antibiotics. Here, the authors use a proteomics approach to study the development of tolerance to the antibiotic colistin in Pseudomonas aeruginosabiofilms, and show that co-treatment with a second compound kills the tolerant cells.