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Subluxation or dislocation of clear or cataractous lens occurs commonly following ocular trauma or in association with systemic or other ocular risk factors. Spontaneous dislocation of lens in the absence of any of these risk factors is very rare. We report a case of bilateral spontaneous posterior dislocation of cataractous lens in a 64-year-old man who was on long-term antipsychotic medications with no preceding history of trauma or other risk factors. Simultaneous bilateral pars plana vitrectomy with lensectomy and glued scleral fixated intraocular lens implantation was done under general anesthesia, following which he had a good visual recovery.