ZIKV can infect human term placentas in the absence of maternal factors
oleh: Diana L. Villazana-Kretzer, Kathryn McGuckin Wuertz, Daniel Newhouse, Jennifer R. Damicis, Elisabeth M. Dornisch, Kathleen M. Voss, Antonio E. Muruato, Jennifer A. Paymaster, Stacey S. Schmiedecke, Sarah M. Edwards, Peter G. Napolitano, Jennifer Tisoncik-Go, Nicholas Ieronimakis, Michael Gale
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-03-01 |
Deskripsi
Villazana-Kretzer et al. compare histology, physiology and gene expression in cotyledons from term placentas perfused with either active or UV-inactivated Zika virus. They show that ZIKV can infect human term placentas in the absence of maternal factors and identify unique transcriptional responses to active ZIKA virus.