Spatial transcriptomics using combinatorial fluorescence spectral and lifetime encoding, imaging and analysis
oleh: Tam Vu, Alexander Vallmitjana, Joshua Gu, Kieu La, Qi Xu, Jesus Flores, Jan Zimak, Jessica Shiu, Linzi Hosohama, Jie Wu, Christopher Douglas, Marian L. Waterman, Anand Ganesan, Per Niklas Hedde, Enrico Gratton, Weian Zhao
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-01-01 |
Deskripsi
Spatial-omics methods with ease-of-use and high multiplexing are in demand. Here the authors report Multi Omic Single-scan Assay with Integrated Combinatorial Analysis (MOSAICA) which uses Spectral and Fluorescence Lifetime Imaging and Microscopy; they apply this to co-detection of mRNA and protein.