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Within disciplines are a set of shared values and thought processes that students must master in order to become participants of that discipline. Information literacy as defined by the ACRL is a set of standards and principles that can apply to all disciplines. In order to produce information literate undergraduates in a given discipline, information literacy standards must be integrated with the values and processes of the discipline. In this study, librarians partnered with faculty in gender studies and molecular biology to integrate information literacy with courses in those areas. Student performance and attitudes improved as a result of the collaboration. This article discusses the collaboration process, the assessment methods and results, and the long-term importance of developing best practices for information literacy integration at the campus level through a disciplinary approach.