Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans
oleh: Kyung-Tae Lee, Yee-Seul So, Dong-Hoon Yang, Kwang-Woo Jung, Jaeyoung Choi, Dong-Gi Lee, Hyojeong Kwon, Juyeong Jang, Li Li Wang, Soohyun Cha, Gena Lee Meyers, Eunji Jeong, Jae-Hyung Jin, Yeonseon Lee, Joohyeon Hong, Soohyun Bang, Je-Hyun Ji, Goun Park, Hyo-Jeong Byun, Sung Woo Park, Young-Min Park, Gloria Adedoyin, Taeyup Kim, Anna F. Averette, Jong-Soon Choi, Joseph Heitman, Eunji Cheong, Yong-Hwan Lee, Yong-Sun Bahn
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-09-01 |
Deskripsi
Cryptococcus neoformans is the leading cause of death by fungal meningoencephalitis. Here, the authors study the roles played by 129 putative kinases in the growth and virulence of C. neoformans, identifying potential targets for development of anticryptococcal drugs.