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A neural m6A/Ythdf pathway is required for learning and memory in Drosophila
oleh: Lijuan Kan, Stanislav Ott, Brian Joseph, Eun Sil Park, Wei Dai, Ralph E. Kleiner, Adam Claridge-Chang, Eric C. Lai
Format: | Article |
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Diterbitkan: | Nature Portfolio 2021-03-01 |
Deskripsi
Epitranscriptomic modifications can regulate learning and memory. Here, the authors provide proteomic and functional analysis of N6-methyladenosine (m6A)-binding proteins in D. melanogaster and unveil behavioral and regulatory defects for m6A/Ythdf mutants.