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Disparities across the world are widening day by day. Children are the most vulnerable population impacted by the disparities. As governments and civil societies are successfully tackling traditional threats to children such as malnutrition, infectious diseases, and inadequate neonatal care, newer threats such as climate change, child trafficking, and childhood obesity are emerging. Threats like the COVID-19 pandemic, although not directly impacting children's health, have caused a significant effect on the delivery of child health services. The present article examines the current and future threats faced by children worldwide and offers solutions to mitigate those threats.