Engineering fungal de novo fatty acid synthesis for short chain fatty acid production
oleh: Jan Gajewski, Renata Pavlovic, Manuel Fischer, Eckhard Boles, Martin Grininger
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-03-01 |
Deskripsi
The production of short chain fatty acids by microorganisms has numerous industrial and biofuel applications. Here the authors reprogrammeS. cerevisiaefatty acid synthase with five mutations to produce C6- and C8-fatty acids and identify thioesterases responsible for hydrolysis of short chain acyl-CoA hydrolysis.