Natural transformation allows transfer of SCCmec-mediated methicillin resistance in Staphylococcus aureus biofilms
oleh: Mais Maree, Le Thuy Thi Nguyen, Ryosuke L. Ohniwa, Masato Higashide, Tarek Msadek, Kazuya Morikawa
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-05-01 |
Deskripsi
SCCmec is a large mobile genetic element that confers resistance to β-lactam antibiotics in methicillin-resistant Staphylococcus aureus. Here, the authors show that biofilm growth conditions enhance the efficiency of natural transformation in S. aureus and allow the transfer of SCCmec to methicillin-sensitive strains.