Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor

oleh: Elsie Diaz, Suraj Adhikary, Armand W. J. W. Tepper, Daniel Riley, Rodrigo Ortiz-Meoz, Daniel Krosky, Christophe Buyck, Carolina Martinez Lamenca, Josep Llaveria, Lichao Fang, Jay H. Kalin, Vincent N. A. Klaren, Shorouk Fahmy, Paul L. Shaffer, Robert Kirkpatrick, Rodrigo J. Carbajo, Maren Thomsen, Antonietta Impagliazzo

Format: Article
Diterbitkan: Nature Portfolio 2022-08-01

Deskripsi

Rational engineering of human spermine oxidase yields crystallizable structures and the design of an allosteric inhibitor.