Phasic dopamine reinforces distinct striatal stimulus encoding in the olfactory tubercle driving dopaminergic reward prediction

oleh: Lars-Lennart Oettl, Max Scheller, Carla Filosa, Sebastian Wieland, Franziska Haag, Cathrin Loeb, Daniel Durstewitz, Roman Shusterman, Eleonora Russo, Wolfgang Kelsch

Format: Article
Diterbitkan: Nature Portfolio 2020-07-01

Deskripsi

It is not entirely understood how network plasticity produces the coding of predicted value during stimulus-outcome learning. Here, the authors reveal a reinforcing loop in distributed limbic circuits, transforming sensory stimuli into reward prediction coding broadcasted by dopamine neurons to the brain.