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This paper focuses on the result of inclined angle on bioconvection of porous media bounded by cavity wall square enclosure filled with both nanofluid and gyrotactic microorganisms passing through the media with pores. The dimensionless velocity, temperature, concentration, and mass transformation equations are solved by using the weighted residual Galerkin’s finite element method. The result of the inclination angle from δ = 0◦ to δ = 180◦ in a square cavity is interpreted. The outcomes of incli-nation on various key parameters, such as Rayleigh number, bioconvective Rayleigh number, Peclet number, Brownian motion, and the ratio of buoy-ancy, are discussed. Furthermore, the mean Nusselt number, Sherwood number, and density number are discussed at vertical walls.