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In this study, 10 essential oils (EOs), from nine plants (<i>Cinnamomum camphora</i>, <i>Curcuma longa</i>, <i>Citrus aurantium</i>, <i>Morinda citrifolia</i>, <i>Petroselinum crispum</i>, <i>Plectranthus amboinicus</i>, <i>Pittosporum senacia</i>, <i>Syzygium coriaceum</i>, and <i>Syzygium samarangense</i>) were assessed for their antimicrobial, antiaging and antiproliferative properties. While only <i>S. coriaceum</i>, <i>P. amboinicus</i> (MIC: 0.50 mg/mL) and <i>M. citrifolia</i> (MIC: 2 mg/mL) EOs showed activity against <i>Cutibacterium acnes</i>, all EOs except S. samarangense EO demonstrated activity against <i>Mycobacterium smegmatis</i> (MIC: 0.125–0.50 mg/mL). The EOs were either fungistatic or fungicidal against one or both tested Candida species with minimum inhibitory/fungicidal concentrations of 0.016–32 mg/mL. The EOs also inhibited one or both key enzymes involved in skin aging, elastase and collagenase (IC₅₀: 89.22–459.2 µg/mL; 0.17–0.18 mg/mL, respectively). Turmerone, previously identified in the <i>C. longa</i> EO, showed the highest binding affinity with the enzymes (binding energy: −5.11 and −6.64 kcal/mol). Only <i>C. aurantium</i> leaf, <i>C. longa</i>, <i>P. amboinicus</i>, <i>P. senacia</i>, <i>S. coriaceum</i>, and <i>S. samarangense</i> EOs were cytotoxic to the human malignant melanoma cells, UCT-MEL1 (IC₅₀: 88.91–277.25 µg/mL). All the EOs, except <i>M. citrifolia</i> EO, were also cytotoxic to the human keratinocytes non-tumorigenic cells, HaCat (IC₅₀: 33.73–250.90 µg/mL). Altogether, some interesting therapeutic properties of the EOs of pharmacological/cosmeceutical interests were observed, which warrants further investigations.