Hyperbranched Molecular Structures with Potential Antiviral Activity: Derivatives of 5,6-Dihydroxyindole-2-Carboxylic Acid
oleh: Alberto Mariani, Stefano Fiori, Ilaria Campesi, Fabio Casu, Mario Sechi
| Format: | Article |
|---|---|
| Diterbitkan: | MDPI AG 2006-12-01 |
Deskripsi
In the search of new HIV-1 integrase (IN) inhibitors, we synthesized a series of multimeric 5,6-dihydroxyindole-2-carboxylic acid (DHICA) derivatives. Preliminary results indicate that hyperbranched architectures could represent a peculiar molecular requisite for the development of new antiviral lead compounds.