STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells
oleh: Lin Jin, Yunjia Chen, David K. Crossman, Arunima Datta, Trung Vu, James A. Mobley, Malay Kumar Basu, Mariangela Scarduzio, Hengbin Wang, Chenbei Chang, Pran K. Datta
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-11-01 |
Deskripsi
STRAP (serine threonine kinase receptor-associated protein) promotes tumorigenicity. Here the authors report that STRAP associates with spliceosome and regulates alternative splicing during embryonic stem cell lineage commitment and early mouse embryo organogenesis.