Intra-pituitary follicle-stimulating hormone signaling regulates hepatic lipid metabolism in mice
oleh: Sen Qiao, Samer Alasmi, Amanda Wyatt, Philipp Wartenberg, Hongmei Wang, Michael Candlish, Debajyoti Das, Mari Aoki, Ramona Grünewald, Ziyue Zhou, Qinghai Tian, Qiang Yu, Viktoria Götz, Anouar Belkacemi, Ahsan Raza, Fabien Ectors, Kathrin Kattler, Gilles Gasparoni, Jörn Walter, Peter Lipp, Patrice Mollard, Daniel J. Bernard, Ersin Karatayli, Senem Ceren Karatayli, Frank Lammert, Ulrich Boehm
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-02-01 |
Deskripsi
Gonadotropes in the pituitary secrete follicle-stimulating hormone and luteinizing hormone to control gonadal function and fertility, but whether they exert actions on extra-gonadal organs is not fully understood. Here the authors report that gonadotropes regulate liver steatosis independent of the ovaries in mice.