Chromium-catalyzed para-selective formation of quaternary carbon centers by alkylation of benzamide derivatives
oleh: Pei Liu, Changpeng Chen, Xuefeng Cong, Jinghua Tang, Xiaoming Zeng
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-11-01 |
Deskripsi
The selective installation of quaternary carbon substituents on arenes is a highly challenging synthetic goal. Here, the authors report a chromium-catalyzed para-selective functionalization of benzamides with tertiary organometallic reagents under mild conditions.