Establishment of a controlled induced pluripotent stem cell line SDPHi004-A from a healthy male donor
oleh: Ziwen Feng, Xiaomeng Yang, Haiyan Zhang, Yi Liu, Wei Song
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2023-09-01 |
Deskripsi
The current induced pluripotent stem cell (iPSCs) line was created from peripheral blood mononuclear cells (PBMCs) obtained from a male donor who was in good health.The iPSCs line SDPHi004-A exhibited the expression of pluripotency markers, absence of free type vectors, maintenance of a normal karyotype, and potential for in vitro trilineage differentiation.This cell line could provide a foundation for disease modeling and facilitate further investigation into the molecular pathogenesis.