Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation
oleh: Diana Langer, Igor Martianov, Daniel Alpern, Muriel Rhinn, Céline Keime, Pascal Dollé, Gabrielle Mengus, Irwin Davidson
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-03-01 |
Deskripsi
The role of TFIID core module TAFs (TATA-binding protein-associated factors) in embryogenesis is unknown. Here, the authors show that Taf4 is essential at mid-gestation and for complete neuronal differentiation of embryonic stem cells, but that Taf4a and Taf4b are redundant at early embryonic stages.