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The fracture of an endodontic instrument is an obstacle in completion of a routine successful pulp space therapy. Ni-Ti instruments corrode when in contact with sodium hypochlorite which leads to their deterioration and ultimately fracture during use. Removal of separated instrument from root canal is often a very difficult procedure. This procedure is more complicated when the instrument separated is closer to the mandibular canal. A case is presented in which a separated hand instrument was retrieved from the mesio buccal of a second molar approximating the mandibular canal root by replantation.