Rapid expansion of Treg cells protects from collateral colitis following a viral trigger
oleh: Michelle Schorer, Katharina Lambert, Nikolas Rakebrandt, Felix Rost, Kung-Chi Kao, Alexander Yermanos, Roman Spörri, Josua Oderbolz, Miro E. Raeber, Christian W. Keller, Jan D. Lünemann, Gerhard Rogler, Onur Boyman, Annette Oxenius, Nicole Joller
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-03-01 |
Deskripsi
Viral infection transiently depletes T regulatory cells (Treg). Here the authors identify a compensatory induced Treg population, which is required to rapidly replenish the Treg niche and suppress microbiota-driven, virus-induced colitis.