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Neospora caninum is a worldwide distributed pathogen which causes abortion in cattle and leading to economic loss in the cattle industry. The aim of this study was to determine the seroprevalence of N. caninum antibodies in cattle in Neishabour (Northeast of Iran). From September 2012 to October 2013 a total of 100 serum samples were analyzed for antibodies against N. caninum antigen using a commercial N. caninum ISCOM ELISA kit. Antibodies to N. caninum were found in 26 of the 100 (26%) sera based on ELISA test results. With regard to seropositivity, no significant difference was observed regarding origin, sex and age (P>0.05).The results showed that N. caninum is relatively prevalent in cattle in the Northeast part of Iran and the evaluation of potential of infection can be useful when considering control programs. Key words: seroprevalence; Neospora caninum; Neishabour; cattle;Iran   SEROPREVALENCA Neospore caninum PRI GOVEDU V SEVERNEM IRANU Neospora caninum je po vsem svetu razširjen patogen, ki povzroča zvrge pri govedu, kar ima za posledico v velike gospodarske izgube v govedoreji. Cilj naše raziskave je bil ugotoviti prekuženost s protitelesi proti N. caninum pri govedu v mestu Neishabour (severovzhodni Iran). Od septembra 2012 do oktobra 2013 je bilo analiziranih skupno 100 vzorcev seruma za protitelesa proti antigenu N. caninum z uporabo komercialno dostopnega kita N. caninum ISCOM ELISA. Rezultati testa ELISA so pokazali protitelesa proti N. caninum v 26 od 100 vzorcev (26 %) serumov. V zvezi s seropozitivnostjo niso opazili pomembnih razlik glede pripadnosti, spola in starosti (p > 0,05). Rezultati so pokazali, da je N. caninum dokaj razširjena pri govedu v severovzhodnem delu Irana in da je ovrednotenje možnosti okužbe lahko koristno pri pripravi kontrolnih programov. Ključne besede: seroprevalenca; Neospora caninum; Neishabour; govedo; Iran