Modeling of waning immunity after SARS-CoV-2 vaccination and influencing factors
oleh: Laura Pérez-Alós, Jose Juan Almagro Armenteros, Johannes Roth Madsen, Cecilie Bo Hansen, Ida Jarlhelt, Sebastian Rask Hamm, Line Dam Heftdal, Mia Marie Pries-Heje, Dina Leth Møller, Kamille Fogh, Rasmus Bo Hasselbalch, Anne Rosbjerg, Søren Brunak, Erik Sørensen, Margit Anita Hørup Larsen, Sisse Rye Ostrowski, Ruth Frikke-Schmidt, Rafael Bayarri-Olmos, Linda Maria Hilsted, Kasper Karmark Iversen, Henning Bundgaard, Susanne Dam Nielsen, Peter Garred
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2022-03-01 |
Deskripsi
This study investigates the dynamics of immunological markers after first SARS-CoV-2 vaccination dose in cohort of healthcare professionals in Denmark. Natural infection was associated with higher antibody responses, and IgG decline varied by age, sex, T-cell response, previous infection, and interval between vaccine doses.