Tracing the origin of heterogeneity and symmetry breaking in the early mammalian embryo
oleh: Qi Chen, Junchao Shi, Yi Tao, Magdalena Zernicka-Goetz
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-05-01 |
Deskripsi
What breaks symmetry in early mammalian embryonic development has been much questioned. Here, Magdalena Zernicka-Goetz and colleagues propose that compartmentalized intracellular reactions generate micro-scale inhomogeneity, which is amplified in the developing embryo, driving pattern formation.