Adult onset pseudohypoparathyroidism type-1b with normal phosphaturic response to exogenous parathyroid hormone
oleh: Sandeep Kharb, Abhay Gundgurthi, M K Dutta, M K Garg
| Format: | Article |
|---|---|
| Diterbitkan: | Wolters Kluwer Medknow Publications 2011-01-01 |
Deskripsi
Pseudohypoparathyroidism type-1b is a hereditary disorder of clinical hypoparathyroidism without AHO phenotype, characterized by blunted nephrogenous cyclic-AMP (cAMP) response to exogenous parathyroid hormone (PTH). Here we report a young adult presenting with hypocalcemic tetany with raised PTH levels. His urinary cAMP response to exogenous PTH (recombinant 1-34) was blunted; however, phosphaturic response was normal.