New Characterization of Multi-Drug Resistance of <i>Streptococcus suis</i> and Biofilm Formation from Swine in Heilongjiang Province of China

oleh: Chun-Liu Dong, Rui-Xiang Che, Tong Wu, Qian-Wei Qu, Mo Chen, Si-Di Zheng, Xue-Hui Cai, Gang Wang, Yan-Hua Li

Format: Article
Diterbitkan: MDPI AG 2023-01-01

Deskripsi

The aim of this study was to investigate the antimicrobial resistance profiles and genotypes of <i>Streptococcus suis</i> in Heilongjiang Province, China. A total of 29 <i>S. suis</i> were isolated from 332 samples collected from 6 pig farms. The results showed that serotypes 2, 4 and 9 were prevalent, and all the clinical isolates were resistant to at least two antibacterial drugs. The most resisted drugs were macrolides, and the least resisted drugs were fluoroquinolones. Resistant genes <i>ermB</i> and <i>aph (3′)-IIIa</i> were highly distributed among the isolates, with the detection rates of 79.31% and 75.86%. The formation of biofilm could be observed in all the isolated <i>S. suis</i>, among which D-1, LL-1 and LL-3 strains formed stronger biofilm structure than other strains. The results indicate that <i>S. suis</i> in Heilongjiang Province presents a multi-drug resistance to commonly used antimicrobial drugs, which was caused by the same target gene, the dissemination of drug resistance genes, and bacterial biofilm.