Automated highly multiplexed super-resolution imaging of protein nano-architecture in cells and tissues

oleh: Maja Klevanski, Frank Herrmannsdoerfer, Steffen Sass, Varun Venkataramani, Mike Heilemann, Thomas Kuner

Format: Article
Diterbitkan: Nature Portfolio 2020-03-01

Deskripsi

Super-resolution imaging of multiple target proteins in the same sample can provide important information of cellular nanostructure, but has not been routinely achieved. Here, the authors present a fully automated 3D STORM approach using a re-staining protocol to image 15 targets in single cells and 16 targets in neuronal tissue.