Unmasking cryptococcal meningitis immune reconstitution inflammatory syndrome in pregnancy induced by HIV antiretroviral therapy with postpartum paradoxical exacerbation
oleh: Reuben Kiggundu, Joshua Rhein, David B. Meya, David R. Boulware, Nathan C. Bahr
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2014-07-01 |
Deskripsi
Cryptococcosis is the most common cause of meningitis in Africa due to the high burden of HIV. Immune reconstitution inflammatory syndrome (IRIS) is a frequent and deadly complication of cryptococcal meningitis. We report a fatal case of cryptococcal-IRIS in a pregnant woman that began after starting antiretroviral therapy (unmasking IRIS) and markedly worsened postpartum after delivery (paradoxical IRIS).