Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions
oleh: Pablo Carravilla, Jakub Chojnacki, Edurne Rujas, Sara Insausti, Eneko Largo, Dominic Waithe, Beatriz Apellaniz, Taylor Sicard, Jean-Philippe Julien, Christian Eggeling, José L. Nieva
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-01-01 |
Deskripsi
The Membrane-Proximal External Region (MPER) of the HIV Env gp41 subunit is a target for broadly neutralizing antibodies. Here, the authors apply super-resolution stimulated emission depletion (STED) microscopy on single virions and provide insights into how the MPER epitope is recognized.