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Coronavirus disease-2019 (COVID-19) is a major global human threat caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Following the first pneumonia case in China in December 2019, humanity faced a dreadful infection in a short period when the World Health Organization declared a pandemic on March 11, 2020. This review aims to look at the epidemiology of COVID-19, the virological characteristics of SARS-CoV-2, and the methods of transmission and prevention.