Find in Library
Search millions of books, articles, and more
Indexed Open Access Databases
Ultrasound assisted site-selective alkynylation of 2,3,5,6-tetrachloropyridines under Pd/CCu catalysis
oleh: Sallagundla Bhavani, Dandela Rambabu, Mandava Venkata Basaveswara Rao, Manojit Pal
Format: | Article |
---|---|
Diterbitkan: | Elsevier 2019-12-01 |
Deskripsi
A convenient synthetic method has been developed for accessing 2,6-dialkynyl-3,5-dichloropyridine derivatives in acceptable to good yields. The methodology involved ultrasound assisted site-selective alkynylation of 2,3,5,6-tetrachloropyridines under Pd/CCu catalysis. A variety of terminal alkynes were employed in this CC coupling reaction to afford the corresponding 2,6-dialkynyl-3,5-dichloropyridine derivatives. Keywords: Pyridine, Alkynes, Pd/C, Ultrasound