Cryo-EM structure of native human thyroglobulin
oleh: Ricardo Adaixo, Eva M. Steiner, Ricardo D. Righetto, Alexander Schmidt, Henning Stahlberg, Nicholas M. I. Taylor
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-01-01 |
Deskripsi
The iodinated thyroglobulin functions as iodine storage and carrier protein and a precursor for thyroid hormone (TH) biogenesis. Here, the authors report the structure of native, fully glycosylated human thyroglobulin, revealing the location of the hTg hormonogenic and glycosylation sites.