Phosphorothioate-DNA bacterial diet reduces the ROS levels in C. elegans while improving locomotion and longevity

oleh: Qiang Huang, Ruohan Li, Tao Yi, Fengsong Cong, Dayong Wang, Zixin Deng, Yi-Lei Zhao

Format: Article
Diterbitkan: Nature Portfolio 2021-11-01

Deskripsi

Qiang Huang et al. fed C. elegans with E. coli containing phosphorothioate (PT) DNA or a control strain and evaluated the impact on animal physiology. They observed that worms fed PT( + ) diets exhibited low reactive oxygen species, more active movement, and a longer lifespan compared to controls, suggesting that PT-DNA may have a positive effect on animal health.