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Diabetes mellitus (Madhumeha) is a metabolic disorder which affects almost all the system of body. patient were registered with the help of Performa prepared for study 100 patient were taken for this observational study Drug Haridra Amalaki yoga were administered in dose of 8 gm per day with water Effect of therapy was assessed by sign symptom and blood sugar level before and after treatment. It was assessed by basis of self formulated scale. All patient were treated with 4 gm of Haridra Amalaki yoga with water twice daily for two month. Periodical checkup and follow up were conducted once in 15 days.Statistical analysis reveal that in the management of Diabetes mellitus the efficacy of Haridra amalaki yoga is effective.By using Haridra amalaki yoga in the management of madhumeha showed a significant result. Haridra Amalaki yoga in management of Madhumeha shows a positive result.