Activated astrocytes attenuate neocortical seizures in rodent models through driving Na+-K+-ATPase
oleh: Junli Zhao, Jinyi Sun, Yang Zheng, Yanrong Zheng, Yuying Shao, Yulan Li, Fan Fei, Cenglin Xu, Xiuxiu Liu, Shuang Wang, Yeping Ruan, Jinggen Liu, Shumin Duan, Zhong Chen, Yi Wang
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-11-01 |
Deskripsi
Neocortical epilepsy is resistant to current treatments. Zhao et al. report that optogenetic stimulation of astrocytes effectively attenuates seizures via driving Na+-K+-ATPase, indicating a potential treatment strategy for intractable epilepsy.