High-resolution cryo-EM structure of urease from the pathogen Yersinia enterocolitica
oleh: Ricardo D. Righetto, Leonie Anton, Ricardo Adaixo, Roman P. Jakob, Jasenko Zivanov, Mohamed-Ali Mahi, Philippe Ringler, Torsten Schwede, Timm Maier, Henning Stahlberg
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-10-01 |
Deskripsi
Urease is a nickel enzyme responsible for catalyzing the conversion of urea into ammonia and carbon dioxide. Here the authors report a high resolution cryo-EM structure of urease from the bacterial pathogen Yersinia enterocolitica, providing a detailed visualization of the urease bimetal active site and a basis for drug development.