Find in Library
Search millions of books, articles, and more
Indexed Open Access Databases
Manganese(III) Acetate-mediated Oxidative Cyclization of a-Methylstyrene and trans-Stilbene with b-Ketosulfones
oleh: Patrice Vanelle, Clémence Tabelé, Christophe Curti, Ahlem Bouhlel
Format: | Article |
---|---|
Diterbitkan: | MDPI AG 2013-04-01 |
Deskripsi
A convenient microwave irradiation protocol was utilized for the synthesis of b-ketosulfones 1–5 in good yields. These sulfones reacted with alkenes through a radical oxidative cyclization mediated by Mn(OAc)3. Dihydrofurans 6–10 were obtained in moderate to good yields starting from 1,1-disubstituted alkenes. Dihydrofurans 11–15 were synthesized in moderate yields and unexpected cyclopropanes 16–19 were obtained in low yields starting from 1,2-disubstituted alkenes. This protocol offers access to various dihydrofurans which could be tested for their antiparasitic potential.