Ultrastructure of influenza virus ribonucleoprotein complexes during viral RNA synthesis

oleh: Masahiro Nakano, Yukihiko Sugita, Noriyuki Kodera, Sho Miyamoto, Yukiko Muramoto, Matthias Wolf, Takeshi Noda

Format: Article
Diterbitkan: Nature Portfolio 2021-07-01

Deskripsi

Nakano et al. use high-speed AFM and cryo-EM to study influenza virus RNA synthesis in vitro. They observe the synthesis of two types of RNA: foldedĀ single stranded RNA associated to an intact viral ribonucleoprotein (vRNP) and looped, double stranded RNA associated with a partially rearranged vRNP structure.