Preferential inhibition of adaptive immune system dynamics by glucocorticoids in patients after acute surgical trauma
oleh: Edward A. Ganio, Natalie Stanley, Viktoria Lindberg-Larsen, Jakob Einhaus, Amy S. Tsai, Franck Verdonk, Anthony Culos, Sajjad Ghaemi, Kristen K. Rumer, Ina A. Stelzer, Dyani Gaudilliere, Eileen Tsai, Ramin Fallahzadeh, Benjamin Choisy, Henrik Kehlet, Nima Aghaeepour, Martin S. Angst, Brice Gaudilliere
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-07-01 |
Deskripsi
Glucocorticoids (GC) are commonly used to suppress undesirable inflammatory responses. Here the authors show, using hi-dimensional flow cytometry data, that GC treatment following major surgeries alters adaptive immunity without significant modulation of innate immune responses or pain/functional impairment.