Design of synthetic epigenetic circuits featuring memory effects and reversible switching based on DNA methylation
oleh: Johannes A. H. Maier, Raphael Möhrle, Albert Jeltsch
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-05-01 |
Deskripsi
Recording systems would allow synthetic organisms to store a ‘memory’ of a past event for future reference. Here the authors design an epigenetic memory system inE. colithat methylates DNA in response to exogenous and endogenous signals.