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Background. Spasticity is a complex topic poorly understood; it can be said that has develops when an inbalance occurs in the excitatory and inhibitory input to a motor neurons which is caused by damage to the spinal cord and/or central nervous system (CNS). Craniosacral therapy (CST) is a manual therapy technique using gentle touch (with a force between 5 to 10 g) to manipulate the synarthrodial joints of the cranium, and also to touch a patient’s spine and pelvis aiming to influence the the pressure and circulatory rhythm of cerebrospinal fluid that surrounds and cushion the brain and the spinal cord. Aims: We propose presentation of a kinesiotherapeutic method named biodynamic craniosacral therapy (BDCST), who may decrease spasticity, the frequency and severity of piramidal spasms in a patient with severe incomplete intens spastic tetraplegia after chronic cervical spinal cord injury (CSCI). Matherials and method. After the approval of Hospital’s Ethics Committee (no. 11/05.08.2017), we are exposeing the case of 35 years old male patient, who has suffered in May 2016 a motorcycle crash with politrauma status including traumatic CSCI (C6, C7 fractures operated ) with tetraplegia C6 neurological level, stage A AIS (initialy), B AIS (now), neurogenic bladder and colon; he was hospitalised in our Clinical Division for 6 weeks, during March and April 2017. The patient has received CST (one sesion daily), posture methods, orthesis therapy and also medicine drugs (anti-spasticity agents, oral anticoagulants, gastroprotectors agents, urinary antiseptics). The anti-spasticity drugs’s dosage remained constant during the treatment. The main clinical outcome measures was: the Ashworth scale (AS) for spasticity of lower limbs, Penn spasm frequency scala (PSFS), Abbrewiated Injury Scale (AIS motor and sensitive). Also it was used secondary outcome scales: Functional Independence Measure (FIM) motor and cognitive, Modified Rankin (Disability) score (mRankin(D)), Glasgow Outcome Scala-Extended (GOS-E). Results. The association of soft osteopathic techniques like CST and anti-spasticity drugs treatment leads to important decreasing of piramidal spasms severity and frequency, also of spasticity’s intensity, wich is beneficial for improvement of daily quality of life. The particularity of case. The analysed case of tetraplegic patient with severe spasticity and severe multiples spasms as number and frequency is a great opportunity to choose a right kinesiological technique to reduces the spastic pattern, despite the fact that’s well known much of the kinesiological techniques may increase spasticity. Conclusions. CST may be beneficial to reduce spasticity, the frequency and severity of muscles spasms in patients with spinal cord injury (SCI).