A common evolutionary origin reveals fundamental principles of protein insertases.
oleh: F-Nora Vögtle, Hans-Georg Koch, Chris Meisinger
| Format: | Article |
|---|---|
| Diterbitkan: | Public Library of Science (PLoS) 2022-03-01 |
Deskripsi
Membrane proteins require protein machineries to insert their hydrophobic transmembrane domains (TMDs) into the lipid bilayer. A functional analysis of protein insertases in this issue of PLOS Biology reveals that the fundamental mechanism of membrane protein insertion is universally conserved.