The intestinal clock drives the microbiome to maintain gastrointestinal homeostasis

oleh: Marjolein Heddes, Baraa Altaha, Yunhui Niu, Sandra Reitmeier, Karin Kleigrewe, Dirk Haller, Silke Kiessling

Format: Article
Diterbitkan: Nature Portfolio 2022-10-01

Deskripsi

Here, Heddes et al. demonstrate a major role for the intestinal circadian clock in driving microbiome dynamics. Microbiota transfer from intestinal clock-deficient mice promotes altered intestinal phenotypes, highlighting the importance of functional intestinal clocks for gastrointestinal homeostasis of the host.